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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HIST1H1B All Species: 17.58
Human Site: S81 Identified Species: 38.67
UniProt: P16401 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.3
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P16401 NP_005313.1 226 22580 S81 Y D V E K N N S R I K L G L K
Chimpanzee Pan troglodytes XP_527284 226 22578 S81 Y D V E K N N S R I K L G L K
Rhesus Macaque Macaca mulatta P40286 208 22075 S82 Y D V E K N N S R I K L S L K
Dog Lupus familis XP_545427 211 21163 S81 Y D V E K N N S R I K L G L K
Cat Felis silvestris
Mouse Mus musculus P43276 223 22558 K81 E K N N S R I K L G L K S L V
Rat Rattus norvegicus P15865 219 21969 K81 E K N N S R I K L G L K S L V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515094 223 22581 K81 E K N N S R I K L G L K S L V
Chicken Gallus gallus P08284 219 22026 I81 V E K N N S R I K L G L K S L
Frog Xenopus laevis P06892 210 21355 S84 Y D V D K N N S R L K L A L K
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P02255 256 26341 P88 C D A Q K L A P F I K K Y L K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus P19375 205 22145 V91 S G S F K V N V Q A A K A Q A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 52.2 89.3 N.A. 90.7 82.3 N.A. 76.1 72.5 61 N.A. N.A. 41 N.A. N.A. 41.5
Protein Similarity: 100 99.5 63.7 91.1 N.A. 92.4 85.8 N.A. 82.7 76.1 68.5 N.A. N.A. 50.7 N.A. N.A. 50.8
P-Site Identity: 100 100 93.3 100 N.A. 6.6 6.6 N.A. 6.6 6.6 80 N.A. N.A. 40 N.A. N.A. 13.3
P-Site Similarity: 100 100 93.3 100 N.A. 6.6 6.6 N.A. 6.6 33.3 93.3 N.A. N.A. 46.6 N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 0 0 10 0 0 10 10 0 19 0 10 % A
% Cys: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 55 0 10 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 28 10 0 37 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 10 0 0 0 0 10 0 0 0 0 0 0 % F
% Gly: 0 10 0 0 0 0 0 0 0 28 10 0 28 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 28 10 0 46 0 0 0 0 0 % I
% Lys: 0 28 10 0 64 0 0 28 10 0 55 46 10 0 55 % K
% Leu: 0 0 0 0 0 10 0 0 28 19 28 55 0 82 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 28 37 10 46 55 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 10 0 0 0 0 10 0 0 0 0 10 0 % Q
% Arg: 0 0 0 0 0 28 10 0 46 0 0 0 0 0 0 % R
% Ser: 10 0 10 0 28 10 0 46 0 0 0 0 37 10 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 10 0 46 0 0 10 0 10 0 0 0 0 0 0 28 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 46 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _